Cryogenic grinding

Cryogenic grinding

• ultra-fine and uniform particle size
• product quality & stability
• high production rates

Particle Size Reduction

Particle size reduction is an important part of pharmaceutical production. Cryogenic grinding with liquid nitrogen is an effective means of obtaining ultra-fine and uniform particle size, while improving product quality and stability as well as production rates. Cryogenic grinding systems combine high-performance fine grinding with cryogenic cooling, helping to provide an inert environment.

PolarFit® cryogenic grinding solutions

It can help you grind more effectively and efficiently, particularly for heat sensitive or tough-to-mill materials. Liquid nitrogen is used to cool down a feed material prior to and/or during milling to either help prevent its melting or decomposition, or achieve embrittlement. Here are some cryogenic grinding benefits:

• Higher yield of particles in your target range
• More uniform particle size distribution
• Higher production rates
• Improved product quality
• Improved process safety due to the nitrogen inertness

About nitrogen

Ultra-cold, inert nitrogen can help reduce heat produced in the grinding process, resulting in high-quality, very fine, uniformly sized particles. Gaseous nitrogen can be used for micronisation applications. Available in medical grade.